CLIMARA®—The Original Once-a-Week Estrogen Therapy (ET) Patch, and the only patch available in 6 dosing options—one may be right for you.
Why? One big reason is that CLIMARA is the only transparent, once-a-week estrogen therapy patch available in 6 dosing options. With 6 available dosage strengths, your healthcare provider can be sure to personalize your treatment by giving you the lowest possible dose needed to treat your symptoms. Plus, you only have to change the CLIMARA patch once a week—no daily pill taking is involved—making it convenient and easy to remember.
All 6 low-dose options provide the estrogen you need at just a fraction of the dose required with a daily estrogen pill. And because the estrogen in the CLIMARA patch is absorbed through the skin, it bypasses your liver.
Estradiol and Dosing Information
The CLIMARA patch continuously releases small amounts of the hormone estradiol through the skin. Estradiol is similar in makeup to the estrogen your ovaries produce before menopause. The dose of estradiol you need will depend upon your individual response and is adjusted by the size of the CLIMARA patch used.
Estrogen therapy has important benefits, but also some risks. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots, and increase your risk of dementia.
You must decide, with your healthcare provider, whether estrogen use is the right choice for you. Check with your healthcare provider each year to be sure you are using the lowest possible dose for the shortest period of time that works for you.
Important Safety Information
What is CLIMARA used for?
CLIMARA is used after menopause to:
- Reduce moderate to severe hot flashes
- Treat moderate to severe dryness, itching, and burning in or around the vagina
- Treat certain conditions in which a young woman's ovaries do not produce enough estrogen naturally
- Help reduce your chances of getting osteoporosis (thin weak bones)
When prescribing solely for vaginal dryness or osteoporosis, other treatments should be considered.
What is the most important information I should know about CLIMARA (an estrogen hormone)?
- Estrogens increase the chances of getting cancer of the uterus.
Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.
- Do not use estrogens with or without progestins to prevent heart disease, heart attacks, strokes, or dementia.
Using estrogens with or without progestins may increase your chances of getting heart attack, strokes, breast cancer, and blood clots. Using estrogens with progestins may increase your risk of dementia.
You and your healthcare provider should talk regularly about whether you still need treatment with CLIMARA.
What is CLIMARA PRO used for?
CLIMARA PRO is used after menopause to:
- Reduce moderate to severe hot flashes.
- Help prevent osteoporosis (thin weak bones).
When prescribing solely for osteoporosis, other treatments should be considered.
What is the most important information I should know about CLIMARA PRO (combination of estrogen and progestin hormones)?
- Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes.
Using estrogens and progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots.
- Do not use estrogens with or without progestins to prevent dementia
Using estrogens with progestins may increase your risk of dementia.
You and your healthcare provider should talk regularly about whether you still need treatment with CLIMARA PRO.
Who should not use CLIMARA and CLIMARA PRO? Do not use CLIMARA PRO if you have had your uterus removed (hysterectomy).
Do not start using CLIMARA if you have unusual vaginal bleeding, currently have or have had certain cancers, had a stroke or heart attack in the past year, currently have or have had blood clots, currently have or have had liver problems, are allergic to CLIMARA or CLIMARA PRO or any of its ingredients, or think you may be pregnant.
What are the warnings of less common but serious side effects of CLIMARA or CLIMARA PRO?
Warnings of less common but serious side effects of CLIMARA or CLIMARA PRO include breast lumps, unusual vaginal bleeding, dizziness and faintness, changes in speech, severe headaches, chest pain, shortness of breath, pains in your legs, changes in vision, and vomiting. Call your healthcare provider right away if you get any of these warning signs, or any other unusual symptom that concerns you.
What are common side effects of CLIMARA or CLIMARA PRO?
Common side effects of CLIMARA include headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps, bloating, nausea and vomiting, and hair loss.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
For important risk and use information, please see the full prescribing information.
